Leaflet COREFLUX 250 ULS soft capsules

Indicated for: vascular disease; thrombosis prevention

Route of administration: oral

Substance: sulodexide (anticoagulant)

ATC: B01AB11 (Blood and blood forming organs | Antithrombotic agents | Heparin group)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Additional monitoring
Additional monitoring

This medicine is subject to additional monitoring.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Bleeding risk
Bleeding risk

This medicine may increase the risk of bleeding.

Sulodexide is a medication primarily used for the treatment and prevention of vascular conditions, especially those involving microcirculation. It is a mixture of glycosaminoglycans, mainly composed of low-molecular-weight heparin and dermatan sulfate, with antithrombotic, profibrinolytic, and vasculoprotective properties.

Sulodexide is indicated for the treatment of chronic venous insufficiency, peripheral arterial disease, diabetic retinopathy, and diabetic nephropathy. It is also used to prevent thrombosis and vascular complications in high-risk patients.

Side effects are rare but may include allergic reactions, gastrointestinal disturbances (such as nausea or diarrhea), and, in very rare cases, bleeding. Patients should inform their doctor about any concurrent anticoagulant therapy, as sulodexide may increase the risk of bleeding.

Sulodexide should be used with caution in patients with coagulation disorders or those taking other anticoagulant medications. Periodic monitoring of coagulation parameters may be necessary during treatment.

COREFLUX 250 ULS soft capsules SANIENCE, sulodexide

General data about COREFLUX 250 ULS

  • Substance: sulodexide
  • Date of latest medicines list: 01-06-2026
  • Product code: W60955001
  • Concentration: 250ULS
  • Pharmaceutical form: soft capsules
  • Quantity: 50
  • Product type: Generic medicine
  • Price: 94.64 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: MIPHARM SPA - ITALIA
  • Holder: SANIENCE S.R.L. - ROMANIA
  • Number: 12805/2019/01
  • Shelf life: 4 years

Pharmaceutical forms available for sulodexide

Concentrations available for sulodexide

  • 250ULS
  • 600ULS/2ml

Compensation lists for COREFLUX 250 ULS Sanience

B - Sublist B with 50% discount from the reference price

Price

Copayment

Patient

94.64 RON

47.32 RON

47.32 RON