Leaflet CO-PRENESSA 2mg / 0.625mg tablets
Indicated for: hypertension
Route of administration: oral
Substance: perindopril + indapamide (ACE inhibitor + diuretic)
ATC: C09BA04 (Cardiovascular system | Ace inhibitors, combinations | Ace inhibitors and diuretics)
Dose adjustment may be needed in kidney disease.
Do not use this medicine during pregnancy.
May lower blood pressure and increase the risk of falls.
This medicine may have important interactions with other medicines.
Periodic laboratory tests may be required during treatment.
This medicine may change blood electrolyte levels.
Perindopril and indapamide are used together in a combination medication for the treatment of high blood pressure (hypertension). This combination combines the effects of an angiotensin-converting enzyme (ACE) inhibitor and a thiazide-like diuretic, providing more effective blood pressure control.
- Perindopril is an ACE inhibitor that works by relaxing blood vessels, reducing vascular resistance, and lowering blood pressure. It also protects the heart and kidneys, helping to prevent cardiovascular complications.
- Indapamide is a thiazide-like diuretic that helps remove excess water and salt from the body through urine, reducing blood volume and lowering blood pressure.
This combination is taken orally, usually once daily, preferably in the morning. It is particularly indicated for patients whose blood pressure is not adequately controlled with a single medication.
Side effects may include dizziness, headache, fatigue, dry cough (due to perindopril), hypokalemia (low potassium levels), muscle cramps, or allergic reactions. It is important to use the medication as prescribed by a healthcare provider, and patients should be regularly monitored to prevent electrolyte imbalances or other complications. Excessive salt intake should be avoided, and patients with kidney or liver conditions should inform their doctor before use.
General data about CO-PRENESSA 2mg / 0.625mg
- Substance: perindopril + indapamide
- Date of last drug list: 01-06-2026
- Commercial code: W65268004
- Concentration: 2mg / 0.625mg
- Pharmaceutical form: tablets
- Quantity: 30
- Product type: generic
- Price: 21.93 RON
- Prescription restrictions: P-6L - Medicines prescription that isn't retained in the pharmacy (can be renewed); the prescription can be used for 6 months from the moment of release.
Pharmaceutical forms available for perindopril + indapamide
Concentrations available for perindopril + indapamide
- 10mg/2.5mg
- 2.5mg/0.625mg
- 2mg+0.625mg
- 2mg/0.625mg
- 4mg/1.25mg
- 5mg/1.25mg
- 8mg/2.5mg
Combinations with other substances
Compensation lists for CO-PRENESSA 2mg / 0.625mg KRKA
B - Sublist B with 50% discount from the reference price
Price
Copayment
Patient
21.93 RON
10.97 RON
10.97 RON