Leaflet CO-KARBIS 16mg / 2.5mg tablets

Indicated for: hypertension

Route of administration: oral

Substance: candesartan cilexetil + indapamide (antihypertensive + diuretic)

ATC: C09DA06 (Cardiovascular system | Angiotensin II receptor blockers (ARBs), combinations | Angiotensin ii receptor blockers (arbs) and diuretics)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Dizziness / vertigo
Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Contraindicated during pregnancy
Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hypotension / fall risk
Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Electrolyte disturbances
Electrolyte disturbances

This medicine may change blood electrolyte levels.

Candesartan cilexetil and indapamide are used together for the treatment of high blood pressure, providing more effective blood pressure control. This combination combines an angiotensin II receptor antagonist (candesartan) and a thiazide-like diuretic (indapamide).

Candesartan helps relax blood vessels, while indapamide reduces blood volume by increasing the elimination of water and salt through urine. This leads to lower blood pressure and a reduced risk of cardiovascular complications.

The medication is taken orally, usually once daily, as directed by a doctor. It is important to monitor blood pressure and electrolyte levels during treatment.

Side effects may include dizziness, fatigue, electrolyte imbalances, or, in rare cases, allergic reactions. Patients should inform their doctor of any unusual symptoms.

General data about CO-KARBIS 16mg / 2.5mg

  • Substance: candesartan cilexetil + indapamide
  • Date of latest medicines list: 01-06-2026
  • Product code: W70913012
  • Concentration: 16mg / 2.5mg
  • Pharmaceutical form: tablets
  • Quantity: 28
  • Product type: Generic medicine
  • Price: 37.46 RON
  • Prescription status: P-6L - Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.

Marketing authorisation

  • Manufacturer: KRKA D.D., NOVO MESTO - SLOVENIA
  • Holder: KRKA, D.D., NOVO MESTO - SLOVENIA
  • Number: 15815/2025/12
  • Shelf life: 2 years

Concentrations available for candesartan cilexetil + indapamide

  • 16mg/2.5mg
  • 8mg/2.5mg

Other substances similar to candesartan cilexetil + indapamide

Compensation lists for CO-KARBIS 16mg / 2.5mg KRKA

D - Sublist D with 20% discount from the reference price

Price

Copayment

Patient

37.46 RON

7.49 RON

29.97 RON