Leaflet CLO-EKARZIN 0.50mg / 10mg cream

Indicated for: inflammatory dermatoses with fungal infection

Route of administration: cutaneous

Substance: betamethasone + clotrimazole (glucocorticoid + azole antifungal)

ATC: D07AC01 (Dermatologicals | Corticosteroids, plain | Corticosteroids, potent (group iii))

Precautions:
Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

The combination of betamethasone and clotrimazole is used to treat inflammatory fungal skin infections such as dermatophytosis, cutaneous candidiasis, and pityriasis versicolor. Betamethasone is a potent corticosteroid that reduces inflammation, itching, and redness, while clotrimazole is a broad-spectrum antifungal that kills fungi by inhibiting the synthesis of their cell membrane.

This combination is available as a cream or ointment and is applied topically to the affected area, usually 1-2 times daily, as directed by a doctor. It is important to avoid using it on broken skin, the face, or sensitive areas unless specifically advised by a doctor.

Side effects may include local irritation, burning sensation, dryness, or, in rare cases, allergic reactions. Prolonged or excessive use of the corticosteroid may lead to skin thinning, stretch marks, or systemic absorption, potentially causing systemic side effects.

This combination is contraindicated in viral infections, cutaneous tuberculosis, hypersensitivity to any of the components, and should be used with caution during pregnancy or breastfeeding. Patients must strictly follow their doctor’s instructions to avoid adverse effects and ensure the effectiveness of the treatment.

General data about CLO-EKARZIN 0.50mg / 10mg

  • Substance: betamethasone + clotrimazole
  • Date of latest medicines list: 01-06-2026
  • Product code: W56622001
  • Concentration: 0.50mg / 10mg
  • Pharmaceutical form: cream
  • Quantity: 1
  • Product type: Generic medicine
  • Price: 27.63 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: ANTIBIOTICE S.A. - ROMANIA
  • Holder: ANTIBIOTICE S.A. - ROMANIA
  • Number: 12069/2019/01
  • Shelf life: 2 years-after packing for marketing;after the first opening-8 weeks

Combinations with other substances