Dose adjustment in renal impairment
Dose adjustment may be needed in kidney disease.
Leaflet CILOPEN 500mg / 500mg powder for solution for infusion
- Product code:
- W54471006
- Quantity:
- 10
- Indicated for:
- bacterial infections
- Route of administration:
- infusion
- Substance:
- imipenem + cilastatin (carbapenem antibiotic + statin lipid-lowering agent)
- ATC
- J01DH51 — Antiinfectives for systemic use | Other beta-lactam antibacterials | Carbapenems
Precautions:
Anaphylaxis
Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.
Colitis / severe diarrhea
Seek medical advice if severe or persistent diarrhea occurs.
Major drug interactions
This medicine may have important interactions with other medicines.
Pregnancy warning
Use during pregnancy only on medical advice.
Seizure risk
This medicine may increase the risk of seizures.
The combination of imipenem and cilastatin is an antibiotic used to treat severe bacterial infections, including respiratory, urinary, abdominal infections, or sepsis. Imipenem is a carbapenem antibiotic, and cilastatin prevents its degradation in the kidneys, enhancing its effectiveness.
The medication is administered via intravenous injection under the supervision of a specialist.
Side effects may include nausea, vomiting, diarrhea, skin rashes, or injection site reactions. In rare cases, severe allergic reactions or seizures may occur.
Patients should inform their doctor about any allergies or other medications they are taking. Pregnant or breastfeeding women should consult a specialist before use.
The medication is administered via intravenous injection under the supervision of a specialist.
Side effects may include nausea, vomiting, diarrhea, skin rashes, or injection site reactions. In rare cases, severe allergic reactions or seizures may occur.
Patients should inform their doctor about any allergies or other medications they are taking. Pregnant or breastfeeding women should consult a specialist before use.
General data about CILOPEN 500mg / 500mg
- Substance:
- imipenem + cilastatin
- Date of latest medicines list:
- 01-06-2026
- Product code:
- W54471006
- Concentration:
- 500mg / 500mg
- Pharmaceutical form:
- powder for solution for infusion
- Quantity:
- 10
- Product type:
- Generic medicine
- Price:
- 416.87 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for imipenem + cilastatin
Concentrations available for imipenem + cilastatin
- 250mg/250mg
- 500mg/500mg
Combinations with other substances
Compensation lists for CILOPEN 500mg / 500mg Terapia
NHP 1.A (C2) - People with HIV/AIDS and post-exposure treatment
- Price
- 416.87 RON
- Copayment
- 308.86 RON
- Patient
- 108.01 RON