Leaflet CARDIOXANE 500mg lyophilisate for solution for injection

Indicated for: protection against chemotherapy or radiotherapy toxicity

Route of administration: injectable

Substance: dexrazoxane (antidote)

ATC: V03AF02 (Various | All other therapeutic products | Detoxifying agents for antineoplastic treatment)

Dexrazoxane is a medication used to protect against anthracycline-induced cardiotoxicity, a type of chemotherapy used in cancer treatment. It works by chelating iron ions, reducing the formation of free radicals that can damage the heart muscle.

The medication is administered intravenously, usually before anthracycline administration, under the supervision of an oncologist.

Side effects may include nausea, vomiting, decreased blood cell counts, or injection site reactions. In rare cases, severe allergic reactions may occur.

Patients should be closely monitored during treatment, and pregnant or breastfeeding women should consult a specialist before use.

General data about CARDIOXANE 500mg

  • Substance: dexrazoxane
  • Date of latest medicines list: 01-07-2013
  • Product code: W00867001
  • Concentration: 500mg
  • Pharmaceutical form: lyophilisate for solution for injection
  • Quantity: 1
  • Product type: Original
  • Prescription status: S - Medicines dispensed with a restricted medical prescription, reserved for use in certain specialized fields.

Concentrations available for dexrazoxane

  • 20mg/ml
  • 500mg