Active substance

Results for the substance glucarpidase

1 result

About this active substance

Glucarpidase is a medication used to reduce toxic levels of methotrexate in the blood in patients receiving this drug for cancer treatment. It is indicated in cases where methotrexate elimination is delayed due to kidney failure.

This medication works by breaking down methotrexate into inactive compounds that are easier to eliminate from the body. It is administered intravenously under medical supervision.

Glucarpidase is generally well-tolerated but may cause side effects such as nausea, vomiting, headaches, or injection site reactions. In rare cases, severe allergic reactions may occur.

It is important to follow your doctor's instructions and undergo regular blood tests to monitor methotrexate levels and kidney function.