Leaflet CAPECITABINA MEDANA 500mg film-coated tablets


Indicated for: cancer

Route of administration: oral

Substance: capecitabine (antimetabolite antineoplastic)

ATC: L01BC06 (Antineoplastic and immunomodulating agents | Antimetabolites | Pyrimidine analogues)

Precautions:
Fertility warning
Fertility warning

This medicine may affect fertility.

Dose adjustment in hepatic impairment
Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Cytotoxic / special handling
Cytotoxic / special handling

Handle with special care.

Contraception required
Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding
Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy
Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis
Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring
Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Severe skin reactions
Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Genetic test recommended
Genetic test recommended

A genetic test may be needed before treatment.

Capecitabine is a chemotherapy medication used to treat various types of cancer, including colon, rectal, breast, and stomach cancer. It is a prodrug, meaning it is converted in the body into its active form, 5-fluorouracil (5-FU), which interferes with DNA and RNA synthesis in cancer cells.

Capecitabine is taken orally in tablet form, making it more convenient than other forms of chemotherapy that require intravenous administration. Treatment is usually given in cycles, and the dosage is adjusted based on the patient's weight, overall health, and the type of cancer being treated.

The medication can be used alone or in combination with other chemotherapy drugs or targeted therapies. It is important for patients to strictly follow their doctor's instructions and report any side effects or unusual symptoms.

Common side effects include nausea, vomiting, diarrhea, fatigue, and hand-foot syndrome (redness, swelling, and pain in the palms and soles). In rare cases, more severe complications such as bone marrow suppression or cardiac toxicity may occur. Regular monitoring is essential to ensure the safety and effectiveness of the treatment.

General data about CAPECITABINA MEDANA 500mg

  • Substance: capecitabine
  • Date of last drug list: 01-07-2013
  • Commercial code: W59061006
  • Concentration: 500mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 120
  • Product type: generic
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Concentrations available for capecitabine

  • 150mg
  • 300mg
  • 500mg