Leaflet ANTALCOL 500mg tablets


Indicated for: alcohol dependence

Route of administration: oral

Substance: disulfiram (enzyme inhibitor)

ATC: N07BB01 (Nervous system | Drugs used in addictive disorders | Drugs used in alcohol dependence)

Disulfiram is a medication used for the treatment of alcohol dependence. It works by inhibiting the enzyme aldehyde dehydrogenase, leading to the accumulation of acetaldehyde in the body when alcohol is consumed, causing unpleasant reactions such as nausea, vomiting, headache, and palpitations.

The medication is taken orally, usually once daily, under medical supervision. It is effective in discouraging alcohol consumption by associating it with unpleasant symptoms.

Side effects may include drowsiness, fatigue, metallic taste, and, in rare cases, liver impairment or severe allergic reactions. It is important to completely avoid alcohol consumption during treatment.

Consult your doctor to discuss the benefits and risks of treatment with Disulfiram. Follow the prescribed dosage and adhere to all medical recommendations.

General data about ANTALCOL 500mg

  • Substance: disulfiram
  • Date of last drug list: 01-06-2026
  • Commercial code: W02618003
  • Concentration: 500mg
  • Pharmaceutical form: tablets
  • Quantity: 30
  • Product type: generic
  • Price: 72.55 RON
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Marketing authorisation

  • Manufacturer: SINTOFARM SA - ROMANIA
  • Holder: SINTOFARM SA - ROMANIA
  • Number: 7923/2006/01
  • Shelf life: 2 years