Active substance

Results for the substance verteporfin

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About this active substance

Verteporfin is a medication used in photodynamic therapy for the treatment of wet age-related macular degeneration (AMD) and other ocular conditions involving abnormal blood vessel growth under the retina. Verteporfin is a photosensitizer that, when activated by laser light, generates reactive oxygen species that selectively destroy abnormal blood vessels.

The medication is administered intravenously, followed by exposure to a laser light source with a specific wavelength that activates verteporfin in the affected area. The procedure is typically performed on an outpatient basis and requires precautions to avoid direct sunlight exposure for several days after treatment.

Common side effects include injection site reactions, blurred vision, eye pain, and photosensitivity. In rare cases, severe adverse reactions such as temporary vision loss or allergic reactions may occur.

Verteporfin is an effective option for managing ocular conditions involving neovascularization, helping to stabilize or improve vision in affected patients.