Medication leaflets

Active substance

Results for the substance varenicline

7 results

About this active substance

Varenicline is a medication used to help people quit smoking. It is a partial agonist of the α4β2 nicotinic acetylcholine receptors, meaning it binds to these receptors and partially activates them, reducing nicotine withdrawal symptoms and cravings. At the same time, varenicline blocks the effects of nicotine from cigarettes, reducing the pleasure associated with smoking.

The medication is taken orally, usually twice daily, and treatment begins one week before the planned quit date. The duration of treatment is typically 12 weeks but may be extended depending on the patient's needs.

Common side effects include nausea, insomnia, abnormal dreams, headaches, and irritability. In rare cases, severe adverse reactions such as mood changes, depression, or suicidal thoughts may occur.

Varenicline is an effective option for smoking cessation, providing pharmaceutical support to individuals seeking to improve their health by quitting this harmful habit.