Medication leaflets

Active substance

Results for the substance trandolapril

13 results

About this active substance

Trandolapril is an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and heart failure. It works by blocking the conversion of angiotensin I to angiotensin II, a hormone that causes vasoconstriction and sodium retention, thereby lowering blood pressure and reducing the workload on the heart.

Trandolapril is administered orally, usually once daily, with the dose adjusted based on patient response and tolerability. It is used both as monotherapy and in combination with other antihypertensive medications.

Common side effects include dizziness, dry cough, fatigue, and nausea. In rare cases, severe adverse reactions such as angioedema, renal failure, or hyperkalemia may occur. Regular monitoring of blood pressure and renal function is essential during treatment.

Trandolapril is an effective and well-tolerated therapeutic option for managing hypertension and heart failure, contributing to the reduction of major cardiovascular events.