Toremifene is a selective estrogen receptor modulator (SERM) used in the treatment of metastatic breast cancer in postmenopausal women. It works by binding to estrogen receptors in tumor cells, inhibiting the effects of estrogen and thereby reducing the growth and proliferation of cancer cells.
Toremifene is administered orally, usually once daily, with the dose adjusted based on patient response and tolerability. It is particularly indicated for patients with hormone receptor-positive tumors.
Common side effects include hot flashes, nausea, fatigue, dizziness, and an increased risk of deep vein thrombosis. In rare cases, severe adverse reactions such as endometrial changes or liver function impairment may occur. Regular monitoring of the patient's condition is essential during treatment.
Toremifene is an effective therapeutic option for managing metastatic breast cancer, contributing to prolonged survival and improved quality of life for patients.