ODOMZO 200mg capsules SUN PHARMACEUTICAL I ORIGINAL MEDICINE
Chemical substance: sonidegib
Active substance
Results for the substance sonidegib
1 result
About this active substance
Sonidegib is an anticancer medicine used in adults with locally advanced basal cell carcinoma, a type of skin cancer that cannot be treated appropriately with surgery or radiotherapy. It is not meant for small, easily removable skin cancers and should be prescribed by a doctor experienced in managing advanced basal cell carcinoma.
Sonidegib blocks the Hedgehog signalling pathway, which can be overactive in basal cell carcinoma and can drive cancer cell growth. By inhibiting this pathway, the medicine may shrink the tumour or slow its progression. It does not always cure the disease, so the doctor will regularly check whether the cancer is responding and whether side effects remain acceptable.
The medicine is taken by mouth as capsules, usually once daily on an empty stomach: at least two hours after food and one hour before the next meal. Capsules should not be opened, crushed or chewed. Tell your doctor about all medicines and supplements you use, because some products can change sonidegib levels and increase side effects or reduce benefit.
Common side effects include muscle spasms or pain, hair loss, taste changes, tiredness, nausea, vomiting, diarrhoea, weight loss, reduced appetite and itching. Contact your doctor quickly if you have severe muscle pain, weakness or dark urine. Sonidegib can cause serious birth defects; it must not be used during pregnancy or breastfeeding, and strict pregnancy prevention is essential.
Sonidegib blocks the Hedgehog signalling pathway, which can be overactive in basal cell carcinoma and can drive cancer cell growth. By inhibiting this pathway, the medicine may shrink the tumour or slow its progression. It does not always cure the disease, so the doctor will regularly check whether the cancer is responding and whether side effects remain acceptable.
The medicine is taken by mouth as capsules, usually once daily on an empty stomach: at least two hours after food and one hour before the next meal. Capsules should not be opened, crushed or chewed. Tell your doctor about all medicines and supplements you use, because some products can change sonidegib levels and increase side effects or reduce benefit.
Common side effects include muscle spasms or pain, hair loss, taste changes, tiredness, nausea, vomiting, diarrhoea, weight loss, reduced appetite and itching. Contact your doctor quickly if you have severe muscle pain, weakness or dark urine. Sonidegib can cause serious birth defects; it must not be used during pregnancy or breastfeeding, and strict pregnancy prevention is essential.