Active substance

Results for the substance sofosbuvir

1 result

About this active substance

Sofosbuvir is an antiviral medication used in the treatment of chronic hepatitis C (HCV). It acts as an NS5B polymerase inhibitor, an enzyme essential for viral RNA replication, thereby blocking the multiplication of the virus in the body.

Sofosbuvir is administered orally, usually once daily, in combination with other antiviral medications such as ribavirin or NS5A inhibitors, depending on the virus genotype and the patient's condition. The duration of treatment ranges from 12 to 24 weeks.

Common side effects include fatigue, headache, nausea, and insomnia. In rare cases, severe adverse reactions such as bradycardia or liver function impairment may occur. It is important for patients to be monitored during treatment to assess therapeutic response and potential side effects.

Sofosbuvir is an essential component of antiviral therapy for hepatitis C, offering high cure rates and good tolerability for most patients.