Medication leaflets

Active substance

Results for the substance sildenafil

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About this active substance

Sildenafil is a medication used to treat erectile dysfunction (impotence) in men and, in some cases, pulmonary arterial hypertension (a condition involving high blood pressure in the blood vessels of the lungs). It belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors, which work by relaxing blood vessels and increasing blood flow to certain areas of the body.

For erectile dysfunction, sildenafil is taken orally, usually 30-60 minutes before sexual activity. Its effects can last up to 4-6 hours, but it does not work without sexual stimulation.

Common side effects include headaches, facial flushing, indigestion, nasal congestion, dizziness, and visual disturbances (such as blurred vision or increased sensitivity to light). In rare cases, it may cause more serious reactions, such as a sudden drop in blood pressure, temporary loss of vision or hearing, or priapism (a prolonged and painful erection requiring immediate medical attention).

Sildenafil is contraindicated in individuals taking nitrates for heart conditions, as the combination can lead to a dangerous drop in blood pressure. It is important for patients to discuss their medical history and any other medications they are taking with their doctor before starting sildenafil treatment.