Medication leaflets

Active substance

Results for the substance rufinamide

3 results

About this active substance

Rufinamide is an antiepileptic medication used in the treatment of seizures associated with Lennox-Gastaut syndrome, a severe form of epilepsy that begins in childhood. It works by prolonging the inactive state of voltage-dependent sodium channels, thereby reducing neuronal excitability and seizure frequency.

Rufinamide is administered orally, usually in tablet or suspension form, and is used as an adjunctive therapy in combination with other antiepileptic drugs. It is effective in reducing tonic-clonic seizures and other types of seizures associated with Lennox-Gastaut syndrome.

Common side effects include drowsiness, dizziness, nausea, and fatigue. In rare cases, severe allergic reactions or cardiac rhythm disturbances may occur. Regular monitoring is essential for dose adjustment and prevention of complications.

Rufinamide is an important therapeutic option for patients with Lennox-Gastaut syndrome, helping to improve seizure control and quality of life.