TRYNGOLZA 80mg solution for injection in pre-filled pen IONIS IRELAND LIMITED
Chemical substance: olezarsen
Active substance
Results for the substance olezarsen
1 result
About this active substance
Olezarsen is a medicine used in adults with familial chylomicronaemia syndrome, a rare genetic condition in which blood triglycerides can become extremely high. Very high triglycerides increase the risk of pancreatitis, a painful and sometimes serious inflammation of the pancreas. The medicine is used together with the diet recommended by your specialist.
It acts on the production of a protein called apolipoprotein C-III, which is involved in fat metabolism. By lowering this protein, olezarsen can help reduce triglyceride levels. It is given as a subcutaneous injection, usually once every four weeks, following the training and schedule provided by your healthcare team.
Common side effects include redness, pain, swelling or skin discolouration at the injection site, joint pain, and a reduced platelet count. Platelets help blood clot. Tell your doctor if you notice unusual bruising, bleeding, small red spots on the skin, fever, or injection-site reactions that are severe or do not settle.
Olezarsen does not replace a strict low-fat diet or regular triglyceride monitoring. Periodic blood tests are needed, including platelet counts and lipid measurements. Tell your doctor if you are pregnant, breastfeeding, or have other important illnesses. Severe abdominal pain with nausea or vomiting may suggest pancreatitis and needs urgent medical assessment.
It acts on the production of a protein called apolipoprotein C-III, which is involved in fat metabolism. By lowering this protein, olezarsen can help reduce triglyceride levels. It is given as a subcutaneous injection, usually once every four weeks, following the training and schedule provided by your healthcare team.
Common side effects include redness, pain, swelling or skin discolouration at the injection site, joint pain, and a reduced platelet count. Platelets help blood clot. Tell your doctor if you notice unusual bruising, bleeding, small red spots on the skin, fever, or injection-site reactions that are severe or do not settle.
Olezarsen does not replace a strict low-fat diet or regular triglyceride monitoring. Periodic blood tests are needed, including platelet counts and lipid measurements. Tell your doctor if you are pregnant, breastfeeding, or have other important illnesses. Severe abdominal pain with nausea or vomiting may suggest pancreatitis and needs urgent medical assessment.