Active substance
Results for the substance icatibant
6 results
About this active substance
Icatibant is a bradykinin B2 receptor antagonist used in the treatment of hereditary angioedema (HAE) caused by C1-esterase inhibitor deficiency. It works by blocking the effects of bradykinin, a peptide responsible for vasodilation and increased vascular permeability, which are key mechanisms in HAE-associated swelling.
It is administered via subcutaneous injection and can rapidly reduce symptoms of acute angioedema episodes, including laryngeal, facial, or abdominal swelling. Compared to other HAE treatments, icatibant has a fast onset of action and effectively shortens the time to symptom relief.
Common side effects include injection site reactions, nausea, headache, and fever. Its use is restricted to patients diagnosed with HAE, as it is not effective for allergic angioedema or angioedema induced by ACE inhibitors.
It is administered via subcutaneous injection and can rapidly reduce symptoms of acute angioedema episodes, including laryngeal, facial, or abdominal swelling. Compared to other HAE treatments, icatibant has a fast onset of action and effectively shortens the time to symptom relief.
Common side effects include injection site reactions, nausea, headache, and fever. Its use is restricted to patients diagnosed with HAE, as it is not effective for allergic angioedema or angioedema induced by ACE inhibitors.
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ICATIBANT ZENTIVA 30mg 10mg/ml solution for injection in pre-filled syringe
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FIRAZYR 30mg 10mg/ml solution for injection in pre-filled syringe SHIRE ORIGINAL MEDICINE
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ICATIBANT ACCORD 30mg 10mg/ml solution for injection in pre-filled syringe
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ICATIBANT TERAPIA 30mg solution for injection in pre-filled syringe
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ICATIBANT UNIVERSAL FARMA 30mg solution for injection in pre-filled syringe