Active substance

Results for the substance ibrutinib

5 results

About this active substance

Ibrutinib is a selective Bruton’s tyrosine kinase (BTK) inhibitor used to treat certain types of hematologic cancers, including chronic lymphocytic leukemia (CLL), mantle cell lymphoma, and Waldenström’s macroglobulinemia. It works by blocking BTK, an enzyme essential for the survival and proliferation of cancer cells.

It is taken orally and is preferred in many cases due to its effectiveness and safety profile compared to conventional therapies.

Ibrutinib significantly improves survival rates in CLL patients and is more effective than traditional treatments such as combination chemotherapy. It is also used as a first-line treatment for certain lymphomas.

However, it can cause side effects, including bleeding, hypertension, arrhythmias, and an increased risk of infections.