Active substance

Results for the substance delamanide

2 results

About this active substance

Delamanid is an antibiotic used for the treatment of multidrug-resistant pulmonary tuberculosis (MDR-TB). It works by inhibiting the synthesis of mycolic acid, essential for the cell wall of Mycobacterium tuberculosis.

The medication is taken orally, usually twice daily, in combination with other antitubercular drugs. Common side effects include nausea, vomiting, headaches, and insomnia.

Delamanid is contraindicated in patients with hypersensitivity to the active substance or severe hepatic conditions. Its use also requires careful monitoring of liver function and the QT interval.

This medication is an important option for managing MDR-TB, helping to increase cure rates and reduce bacterial resistance.