Active substance

Results for the substance defibrotide

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About this active substance

Defibrotide is a medication used for the treatment of hepatic veno-occlusive disease (VOD), a serious complication that can occur after hematopoietic stem cell transplantation. It works by protecting endothelial cells and reducing inflammation and excessive blood clotting in the blood vessels.

The medication is administered intravenously and is particularly indicated for patients with severe VOD. It is effective in improving liver function and reducing mortality associated with this condition.

Side effects may include bleeding, hypotension, nausea, and diarrhea. Close monitoring of liver function and coagulation parameters is essential during treatment.

Consult your doctor to discuss the benefits and risks of treatment with Defibrotide. This medication must be administered under the supervision of a specialist.