Active substance

Results for the substance clascoterone

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About this active substance

Clascoterone is a topical treatment for acne vulgaris, used as a skin cream. It works by blocking androgen receptors in sebaceous glands and hair follicles, reducing hormonal signals that can promote excess oil and inflammation. It may be prescribed for adolescents or adults after dermatology assessment.

The cream is usually applied twice daily in a thin layer to affected areas on clean, dry skin. Avoid the eyes, lips, inside of the nose, mucous membranes and broken skin. Wash your hands after use. Improvement is gradual; applying too much or too often is unlikely to work faster and may increase irritation.

Side effects are usually local: redness, dryness, scaling, itching, stinging or burning at the application site. Less often, stronger irritation or swelling can occur. Contact your clinician if symptoms are severe or persistent, or if blisters, marked crusting or allergy signs appear. Strong exfoliants or multiple acne treatments may need adjustment.

Clascoterone is not an antibiotic and does not treat every cause of acne, but it can be useful in a complete treatment plan. Tell your clinician about other creams, medicines or supplements, and ask for advice if pregnant, planning pregnancy or breastfeeding. Use non-comedogenic skin care and sun protection, and avoid squeezing spots to limit inflammation and scarring.