Active substance
Results for the substance carglumic acid
2 results
About this active substance
Carglumic acid is used to treat hyperammonemia, a condition caused by excessive ammonia accumulation in the blood. It is specifically indicated for patients with N-acetylglutamate synthase (NAGS) deficiency, an enzyme essential for the urea cycle, which helps remove ammonia from the body.
Carglumic acid stimulates the urea cycle, facilitating the conversion of toxic ammonia into urea, which is excreted in the urine. It is administered orally, usually in the form of dispersible tablets, and the dosage is adjusted based on blood ammonia levels.
Side effects may include nausea, vomiting, diarrhea, or abdominal pain. Regular monitoring of ammonia levels and liver function is essential during treatment. The medication should be used as directed by a doctor, and the treatment is tailored to each patient.
Carglumic acid stimulates the urea cycle, facilitating the conversion of toxic ammonia into urea, which is excreted in the urine. It is administered orally, usually in the form of dispersible tablets, and the dosage is adjusted based on blood ammonia levels.
Side effects may include nausea, vomiting, diarrhea, or abdominal pain. Regular monitoring of ammonia levels and liver function is essential during treatment. The medication should be used as directed by a doctor, and the treatment is tailored to each patient.