Hepatotoxicity
This medicine may affect the liver.
Medicine information ZEVASTOR DUO 20mg / 10mg tablets
- Product code:
- W71602002
- Quantity:
- 30
- Indicated for:
- dyslipidemia
- Route of administration:
- oral
- Substance:
- rosuvastatin + ezetimibe (statin lipid-lowering agent+lipid-lowering agent)
- ATC
- C10BA06 — Cardiovascular system | Lipid modifying agents | Lipid modifying agents, combinations | Combinations of various lipid modifying agents
The combination of rosuvastatin and ezetimibe is used to treat hypercholesterolemia (high cholesterol levels) and to prevent cardiovascular diseases in high-risk patients. It combines two complementary mechanisms to lower LDL cholesterol ('bad cholesterol') levels and improve the lipid profile.
- Rosuvastatin is an HMG-CoA reductase inhibitor (statin) that reduces cholesterol synthesis in the liver, lowering LDL cholesterol and triglycerides while increasing HDL cholesterol ('good cholesterol').
- Ezetimibe works by inhibiting the absorption of cholesterol in the intestines, reducing the amount of cholesterol that enters the bloodstream.
This combination is indicated for patients who cannot achieve target cholesterol levels with statins alone or who require more intensive LDL cholesterol reduction. The medication is taken orally, usually once daily, and the dose is adjusted based on the patient’s needs.
Common side effects include muscle pain, headache, nausea, fatigue, and abdominal discomfort. In rare cases, more serious reactions such as liver dysfunction or rhabdomyolysis (a condition involving muscle tissue breakdown) may occur. Regular monitoring of liver function and lipid levels is essential during treatment.
Treatment with rosuvastatin and ezetimibe should be administered under the supervision of a doctor, and patients should follow a low-fat, low-cholesterol diet to maximize the benefits of therapy.
- Rosuvastatin is an HMG-CoA reductase inhibitor (statin) that reduces cholesterol synthesis in the liver, lowering LDL cholesterol and triglycerides while increasing HDL cholesterol ('good cholesterol').
- Ezetimibe works by inhibiting the absorption of cholesterol in the intestines, reducing the amount of cholesterol that enters the bloodstream.
This combination is indicated for patients who cannot achieve target cholesterol levels with statins alone or who require more intensive LDL cholesterol reduction. The medication is taken orally, usually once daily, and the dose is adjusted based on the patient’s needs.
Common side effects include muscle pain, headache, nausea, fatigue, and abdominal discomfort. In rare cases, more serious reactions such as liver dysfunction or rhabdomyolysis (a condition involving muscle tissue breakdown) may occur. Regular monitoring of liver function and lipid levels is essential during treatment.
Treatment with rosuvastatin and ezetimibe should be administered under the supervision of a doctor, and patients should follow a low-fat, low-cholesterol diet to maximize the benefits of therapy.
General data about ZEVASTOR DUO 20mg / 10mg
- Substance:
- rosuvastatin + ezetimibe
- Date of latest medicines list:
- 01-10-2026
- Product code:
- W71602002
- Strength:
- 20mg / 10mg
- Pharmaceutical form:
- tablets
- Quantity:
- 30
- Product type:
- Generic medicine
- Price:
- 75.68 RON
- Prescription status:
- P-6L — Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.
Pharmaceutical forms available for rosuvastatin + ezetimibe
Strengths available for rosuvastatin + ezetimibe
- 10mg/10mg
- 15mg/10mg
- 20mg/10mg
- 40mg/10mg
- 5mg/10mg
Official documents
Professional information (SmPC) - Romanian
Patient leaflet - Romanian
Packaging and labelling information - Romanian
The correspondence between the document and the displayed text is unconfirmed.
- Source institution
- ANMDMR
- Document language
- Romanian
Warnings:
Major drug interactions
This medicine may have important interactions with other medicines.
Myopathy / rhabdomyolysis
Seek medical advice if unexplained muscle pain occurs.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Pregnancy warning
Use during pregnancy only on medical advice.
Reimbursement lists for ZEVASTOR DUO 20mg / 10mg Antibiotice
B - Sublist B with 50% discount from the reference price
- Price
- 75.68 RON
- Copayment
- 35.11 RON
- Patient payment
- 40.57 RON