J02AC03 • voriconazole • Antiinfectives for systemic use | Antimycotics for systemic use | Triazole derivatives
Voriconazole is an antifungal medication used to treat severe fungal infections, such as invasive aspergillosis, esophageal candidiasis, and other fungal infections caused by Candida or Fusarium species. It belongs to the triazole class and works by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane, leading to fungal destruction.
Voriconazole is particularly indicated for immunocompromised patients, such as those with organ transplants, cancer, or other conditions that weaken the immune system. It is available in tablet form, oral suspension, or intravenous injection, and the dosage is adjusted based on the patient’s weight and the severity of the infection.
Common side effects include nausea, vomiting, abdominal pain, skin rashes, visual disturbances (such as blurred vision or light sensitivity), and elevated liver enzymes. Rarely, more serious reactions such as severe hepatotoxicity, allergic reactions, or cardiac arrhythmias may occur.
Treatment with voriconazole requires careful monitoring, including regular liver and kidney function tests. Patients should avoid prolonged sun exposure, as voriconazole can increase skin sensitivity to UV radiation. The medication should be taken as prescribed by a doctor, and dose adjustments should be made cautiously.
Substance: voriconazole
Date of last drug list: 01-06-2025
Commercial code: W62122001
Concentration: 200mg
Pharmaceutical form: powder infusion solution
Quantity: 1
Product type: generic
Price: 511.40 RON
Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).
Manufacturer: FRESENIUS KABI DEUTSCHLAND GMBH - GERMANIA
Holder: FRESENIUS KABI ROMANIA S.R.L. - ROMANIA
Number: 13269/2020/01
Shelf life: 3 years-after packing for marketing;after reconstitution-it is used immediately
G10 (C1) - Leukemias, lymphomas and spinal cord aplasia, tumors
Price
Copayment
Patient
511.40 RON
472.70 RON
38.70 RON
GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)
Price
Copayment
Patient
511.40 RON
472.70 RON
38.70 RON
NHP 1.A (C2) - People with HIV/AIDS and post-exposure treatment
Price
Copayment
Patient
511.40 RON
472.70 RON
38.70 RON
NHP 9.4 (C2) - Kidney transplant, combined kidney and pancreas transplant
Price
Copayment
Patient
511.40 RON
472.70 RON
38.70 RON
NHP 9.5 (C2) - Pancreatic cell transplantation
Price
Copayment
Patient
511.40 RON
472.70 RON
38.70 RON
NHP 9.7 (C2) - Outpatient treatment of transplant patients
Price
Copayment
Patient
511.40 RON
472.70 RON
38.70 RON