Indicated for: heart failure
Route of administration: infusion
Substance: milrinone (cardiotonic)
ATC: C01CE02 (Cardiovascular system | Cardiac stimulants excluding cardiac glycosides | Phosphodiesterase inhibitors)
Milrinone is a phosphodiesterase type 3 inhibitor used for the treatment of acute decompensated heart failure. It works by increasing myocardial contractility and causing vasodilation, thereby improving cardiac function.
The medication is administered via intravenous infusion, with the dose adjusted based on the patient's weight and hemodynamic response. Common side effects include hypotension, arrhythmias, and headaches.
Milrinone is contraindicated in patients with hypersensitivity to the active substance or severe obstructive valvular conditions. Its use also requires careful monitoring of cardiac function and blood pressure.
This medication is an important option for patients with severe heart failure, helping to stabilize hemodynamic status and alleviate symptoms.