Leaflet TWILEV 2.5mg / 5mg film-coated tablets


Indicated for: arterial hypertension

Route of administration: oral

Substance: ramipril + nebivolol (ACE inhibitor + beta blocker)

Precautions:
Dizziness / vertigo
Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Contraindicated during pregnancy
Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hypotension / fall risk
Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Elderly warning
Elderly warning

Older people may have an increased risk of side effects.

Electrolyte disturbances
Electrolyte disturbances

This medicine may change blood electrolyte levels.

Ramipril + nebivolol is a combination used to treat high blood pressure in adults, especially when one medicine alone is not enough or when the doctor wants two complementary mechanisms. Together they help lower blood pressure and reduce the workload on the heart.

It is taken by mouth, usually once daily, exactly as prescribed. The tablet or capsule should be taken regularly, preferably at the same time each day. Treatment should not be stopped suddenly unless a doctor tells you to, because blood pressure may rise again and heart symptoms can worsen. The dose is chosen according to blood pressure, pulse rate, age, kidney function and other medicines.

Possible side effects include dizziness, tiredness, headache, a slow heartbeat, low blood pressure, dry cough, nausea, digestive discomfort, increased potassium levels and changes in kidney function tests. Your doctor may recommend blood tests and home blood-pressure monitoring.

Seek medical advice urgently if you develop swelling of the face, lips, tongue or throat, breathing difficulty, fainting, very slow heartbeat, chest pain, markedly reduced urination or signs of allergy. This treatment must not be used during pregnancy and needs caution in people with severe asthma, certain heart rhythm disorders, unstable heart failure, significant kidney disease or dehydration.

General data about TWILEV 2.5mg / 5mg

  • Substance: ramipril + nebivolol
  • Commercial code: W71929001
  • Concentration: 2.5mg / 5mg
  • Pharmaceutical form: film-coated tablets
  • Product type: generic
  • Prescription restrictions: P-6L - Medicines prescription that isn't retained in the pharmacy (can be renewed); the prescription can be used for 6 months from the moment of release.

Marketing authorisation

  • Manufacturer: SANECA PHARMACEUTICALS, A.S. - SLOVACIA
  • Holder: MENARINI INTERNATIONAL OPERATION LUXEMBOURG S.A. - SLOVACIA
  • Number: 16644/2026/01
  • Shelf life: 2 years