Major drug interactions
This medicine may have important interactions with other medicines.
Leaflet TROMBEX 75mg film-coated tablets
- Product code:
- W54317002
- Quantity:
- 30
- Indicated for:
- prevention of atherothrombotic events
- Route of administration:
- oral
- Substance:
- clopidogrel (antiplatelet agent)
- ATC
- B01AC04 — Blood and blood forming organs | Antithrombotic agents | Antithrombotic agents | Platelet aggregation inhibitors excl. heparin
Precautions:
Bleeding risk
This medicine may increase the risk of bleeding.
Clopidogrel is an antiplatelet medication used to prevent blood clots (thrombosis) in cardiovascular conditions. It is particularly indicated for patients at high risk of thrombotic events, such as myocardial infarction, ischemic stroke, or peripheral arterial disease. It is also used after procedures like coronary angioplasty or stent implantation to prevent stent occlusion.
Clopidogrel works by inhibiting platelet aggregation, blocking P2Y12 receptors on the surface of platelets. This mechanism prevents platelets from sticking together, reducing the risk of blood clot formation.
The medication is taken orally, usually once daily, and the dosage is determined by the doctor based on the condition being treated. It is important for patients to take clopidogrel as prescribed and not to stop the treatment without medical advice, as this may increase the risk of thrombotic events.
Common side effects include bleeding (e.g., gums, nose, or gastrointestinal tract), bruising, and gastrointestinal issues such as diarrhea or abdominal pain. Rarely, allergic reactions or a serious condition called thrombotic thrombocytopenic purpura (TTP) may occur.
Patients should inform their doctor about other medications they are taking, as clopidogrel can interact with certain treatments, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or anticoagulants, increasing the risk of bleeding.
Clopidogrel works by inhibiting platelet aggregation, blocking P2Y12 receptors on the surface of platelets. This mechanism prevents platelets from sticking together, reducing the risk of blood clot formation.
The medication is taken orally, usually once daily, and the dosage is determined by the doctor based on the condition being treated. It is important for patients to take clopidogrel as prescribed and not to stop the treatment without medical advice, as this may increase the risk of thrombotic events.
Common side effects include bleeding (e.g., gums, nose, or gastrointestinal tract), bruising, and gastrointestinal issues such as diarrhea or abdominal pain. Rarely, allergic reactions or a serious condition called thrombotic thrombocytopenic purpura (TTP) may occur.
Patients should inform their doctor about other medications they are taking, as clopidogrel can interact with certain treatments, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or anticoagulants, increasing the risk of bleeding.
General data about TROMBEX 75mg
- Substance:
- clopidogrel
- Date of latest medicines list:
- 01-06-2026
- Product code:
- W54317002
- Concentration:
- 75mg
- Pharmaceutical form:
- film-coated tablets
- Quantity:
- 30
- Product type:
- Generic medicine
- Price:
- 22.80 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for clopidogrel
Concentrations available for clopidogrel
- 300mg
- 75mg
Combinations with other substances
Compensation lists for TROMBEX 75mg Zentiva
B - Sublist B with 50% discount from the reference price
- Price
- 22.80 RON
- Copayment
- 11.40 RON
- Patient
- 11.40 RON
G3 (C1) - Patients with percutaneous interventional procedures
- Price
- 22.80 RON
- Copayment
- 22.80 RON
- Patient
- 0.00 RON
GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)
- Price
- 22.80 RON
- Copayment
- 22.80 RON
- Patient
- 0.00 RON