Leaflet TOBREX 2x 0.3% ophthalmic drops solution
Indicated for: bacterial infections
Route of administration: ophthalmic
Substance: tobramycin (aminoglycoside antibiotic)
ATC: S01AA12 (Sensory organs | Antiinfectives | Antibiotics)
Dose adjustment may be needed in kidney disease.
Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.
Seek medical advice if severe or persistent diarrhea occurs.
This medicine may affect the kidneys.
This medicine may affect hearing or balance.
Use during pregnancy only on medical advice.
Tobramycin is an aminoglycoside antibiotic used to treat severe bacterial infections caused by Gram-negative bacteria, such as Pseudomonas aeruginosa. It is commonly used for respiratory infections, skin infections, urinary tract infections, and eye infections. Tobramycin works by inhibiting bacterial protein synthesis, leading to bacterial destruction.
The medication is available in various forms, including injectable solutions, eye drops, and inhalation solutions (for pulmonary infections, such as those associated with cystic fibrosis). The dosage and route of administration depend on the type and severity of the infection.
Common side effects include local irritation (for topical use), nausea, vomiting, and skin rashes. When administered systemically, tobramycin can cause serious adverse effects, such as ototoxicity (hearing damage), nephrotoxicity (kidney damage), and neurotoxicity. For this reason, careful monitoring of kidney function and hearing is required during treatment. Tobramycin is contraindicated in patients with hypersensitivity to aminoglycosides.
General data about TOBREX 2x 0.3%
- Substance: tobramycin
- Date of latest medicines list: 01-02-2023
- Product code: W42218001
- Concentration: 0.3%
- Pharmaceutical form: ophthalmic drops solution
- Quantity: 1
- Product type: Original
- Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for tobramycin
Concentrations available for tobramycin
- 0.3%
- 300mg
- 300mg/5ml
- 3mg/g
- 3mg/ml
- 40mg/ml