TARKA 180mg / 2mg prolonged-release tablets medication leaflet

C09BB10 • verapamil + trandolapril • Cardiovascular system | Ace inhibitors, combinations | Ace inhibitors and calcium channel blockers

The combination of verapamil and trandolapril is used for the treatment of hypertension and cardiovascular diseases, particularly in patients who require both a calcium channel blocker and an angiotensin-converting enzyme (ACE) inhibitor. Verapamil is a calcium channel blocker that relaxes blood vessels and reduces heart rate, improving blood flow and lowering blood pressure. Trandolapril is an ACE inhibitor that reduces the production of angiotensin II, a hormone that causes blood vessel constriction.

This combination is administered orally, usually once daily, and the dosage is adjusted based on the patient's response and blood pressure levels. It is important for patients to adhere to the treatment and regularly monitor their blood pressure.

Common side effects include dizziness, headaches, nausea, and fatigue. In rare cases, severe adverse reactions such as severe hypotension, hyperkalemia, or allergic reactions may occur.

The combination of verapamil and trandolapril provides an effective option for managing hypertension and cardiovascular diseases, helping to reduce the risk of complications such as myocardial infarction or stroke.