Leaflet TALIXIMUN 5mg capsules


Indicated for: prevention of transplant rejection

Route of administration: oral

Substance: tacrolimus (immunosuppressant)

ATC: L04AD02 (Antineoplastic and immunomodulating agents | Immunosuppressants | Calcineurin inhibitors)

Precautions:
Avoid grapefruit
Avoid grapefruit

Avoid grapefruit and grapefruit juice.

Avoid live vaccines
Avoid live vaccines

Avoid live vaccines during treatment if contraindicated.

Immunosuppression / infection risk
Immunosuppression / infection risk

This medicine may increase the risk of infections.

Narrow therapeutic index
Narrow therapeutic index

The dose must be followed strictly.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Tacrolimus is an immunosuppressive medication used to prevent organ rejection in transplant recipients, such as kidney, liver, or heart transplants. It works by inhibiting the activity of T-cells in the immune system, thereby reducing the immune response that could attack the transplanted organ.

Tacrolimus is available in capsules, ointments, and injectable solutions. For transplants, it is administered long-term to ensure the proper functioning of the transplanted organ. Additionally, tacrolimus ointment is used to treat severe atopic dermatitis when other treatments are ineffective.

The medication requires careful monitoring, as high levels can lead to toxicity, while low levels may increase the risk of organ rejection. Common side effects include tremors, headaches, high blood pressure, nausea, and an increased risk of infections.

Tacrolimus should be used as directed by a healthcare provider, and patients are advised to avoid excessive sun exposure, as the medication can increase skin sensitivity.

General data about TALIXIMUN 5mg

  • Substance: tacrolimus
  • Date of last drug list: 01-07-2013
  • Commercial code: W56394001
  • Concentration: 5mg
  • Pharmaceutical form: capsules
  • Quantity: 30
  • Product type: generic
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Concentrations available for tacrolimus

  • 0.03%
  • 0.1%
  • 0.2mg
  • 0.5mg
  • 1mg
  • 2mg
  • 3mg
  • 5mg
  • 5mg/ml