Leaflet TACHOCOMB sponge

Indicated for: bleeding; coagulation disorders

Route of administration: local hemostasis

Substance: fibrinogen + thrombin (hemostatic agent + anticoagulant)

ATC: B02BC30 (Blood and blood forming organs | Vitamin k and other hemostatics | Local hemostatics)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Additional monitoring
Additional monitoring

This medicine is subject to additional monitoring.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Bleeding risk
Bleeding risk

This medicine may increase the risk of bleeding.


Fibrinogen and thrombin are two essential substances involved in the blood clotting process. The combination of fibrinogen and thrombin is used in medicine to stop bleeding, especially during surgical procedures or in cases of severe injuries. This mixture helps form a blood clot quickly, protecting the affected area and promoting healing.

The combination of fibrinogen and thrombin is applied locally, directly to the wound or bleeding surface, in the form of powder, gel, or special dressing. The doctor or medical staff applies this combination to control bleeding and reduce the risk of complications. Its use is safe when performed under medical supervision.

Side effects are rare but may include local allergic reactions, redness, swelling, or, in very rare cases, systemic reactions. It is important to inform your doctor if you have a history of allergies or bleeding disorders. Careful monitoring after application is recommended to prevent any complications.

Fibrinogen and thrombin are valuable tools in controlling bleeding, contributing to the safety of medical procedures and the rapid recovery of patients. Following medical instructions and communicating with your care team are essential for effective and safe treatment.

General data about TACHOCOMB

  • Substance: fibrinogen + thrombin
  • Date of latest medicines list: 01-07-2013
  • Product code: W01711001
  • Pharmaceutical form: sponge
  • Quantity: 1
  • Product type: Original
  • Prescription status: S - Medicines dispensed with a restricted medical prescription, reserved for use in certain specialized fields.

Pharmaceutical forms available for fibrinogen + thrombin