Leaflet SYNACHTEN DEPOT 1mg / ml injection suspension


Indicated for: adrenal cortex function testing

Route of administration: injectable

Substance: tetracosactide (diagnostic agent)

ATC: H01AA02 (Systemic hormonal preparations, excluding sex hormones and insulins | Anterior pituitary lobe hormones and analogues | Acth)

Tetracosactide is a medication primarily used for diagnosing adrenal insufficiency and treating certain severe inflammatory conditions. It is a synthetic analog of adrenocorticotropic hormone (ACTH), which stimulates the adrenal glands to produce corticosteroids, such as cortisol.

For diagnostic purposes, tetracosactide is used in the ACTH stimulation test to assess adrenal gland function. This test helps identify primary adrenal insufficiency (Addison's disease) or secondary insufficiency (caused by pituitary dysfunction). Therapeutically, tetracosactide may be used to treat inflammatory conditions such as rheumatoid arthritis or ulcerative colitis when other treatments are ineffective.

The medication is administered via intramuscular or intravenous injection under medical supervision. Common side effects include increased blood pressure, fluid retention, hyperglycemia, and, rarely, allergic reactions. It is contraindicated in patients with active systemic infections, severe hypertension, or decompensated heart failure.

General data about SYNACHTEN DEPOT 1mg / ml

  • Substance: tetracosactide
  • Date of last drug list: 01-03-2026
  • Commercial code: W70922001
  • Concentration: 1mg / ml
  • Pharmaceutical form: injection suspension
  • Quantity: 1
  • Product type: generic
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Marketing authorisation

  • Manufacturer: ALFASIGMA S.P.A. - ITALIA
  • Holder: CN UNIFARM S.A. - ROMANIA
  • Number: 1034/2025/01

Pharmaceutical forms available for tetracosactide

Concentrations available for tetracosactide

  • 0.25mg/1ml
  • 1mg/ml