Leaflet SOLPADEINE DUO 500mg / 12.8mg film-coated tablets


Indicated for: pain; fever

Substance: paracetamol + codeine (analgesic and antipyretic + opioid analgesic)

ATC: N02BE51 (Nervous system | Other analgesics and antipyretics | Anilides)

Paracetamol + codeine is a combination medication used to treat moderate to severe pain that cannot be managed with paracetamol alone. Paracetamol acts as an analgesic and antipyretic, reducing pain and fever, while codeine, a mild opioid, enhances the analgesic effect of paracetamol by acting on pain receptors in the central nervous system.

This combination is commonly used for severe headaches, dental pain, postoperative pain, or other types of acute or chronic pain. It is important to use this medication for short-term treatment, as codeine can cause dependency if taken for extended periods.

Side effects may include drowsiness, dizziness, constipation, nausea, or, in rare cases, allergic reactions. Overuse can lead to liver damage (due to paracetamol) or codeine dependency. It is essential to take this combination as prescribed by a doctor and avoid excessive use.

General data about SOLPADEINE DUO 500mg / 12.8mg

  • Substance: paracetamol + codeine
  • Date of last drug list: 01-04-2026
  • Commercial code: W63608002
  • Concentration: 500mg / 12.8mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 10
  • Product type: generic
  • Prescription restrictions: OTC - Over the Counter = medicines that do not require a prescription.

Marketing authorisation

  • Manufacturer: SWISS CAPS GMBH - GERMANIA
  • Holder: HIPOCRATE 2000 S.R.L. - ROMANIA
  • Number: 9795/2017/02
  • Shelf life: 2 years

Pharmaceutical forms available for paracetamol + codeine

Concentrations available for paracetamol + codeine

  • 1000mg/60mg
  • 500mg/12.8mg
  • 500mg/30mg
  • 500mg/60mg