Leaflet SINDOVIN 1mg powder for solution for injection / infusion

Product code:
W52220001
Quantity:
1
Indicated for:
cancer
Route of administration:
injectable / infusion
Substance:
vincristine (antineoplastic agent)
ATC
L01CA02 — Antineoplastic and immunomodulating agents | Plant alkaloids and other natural products | Vinca alkaloids and analogues

Precautions:

Fertility warning

Fertility warning

This medicine may affect fertility.

Dose adjustment in hepatic impairment

Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Cytotoxic / special handling

Cytotoxic / special handling

Handle with special care.

Contraception required

Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding

Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy

Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hepatotoxicity

Hepatotoxicity

This medicine may affect the liver.

Major drug interactions

Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis

Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring

Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests

Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Neuropathy / neurotoxicity

Neuropathy / neurotoxicity

This medicine may affect the nerves or nervous system.

Severe skin reactions

Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Vincristine is a chemotherapy medication used for the treatment of various types of cancer, including acute lymphoblastic leukemia, Hodgkin's lymphoma, non-Hodgkin's lymphoma, and Ewing's sarcoma. It belongs to the vinca alkaloid class and works by inhibiting microtubule formation, leading to the arrest of cell division and tumor cell death.

Vincristine is administered intravenously, usually once a week, and the dosage is adjusted based on body weight and patient response. Treatment is conducted under the supervision of an oncologist, and patients are monitored for signs of toxicity.

Common side effects include peripheral neuropathy, constipation, hair loss, nausea, and fatigue. In rare cases, severe adverse reactions such as liver function impairment or bone marrow depression may occur.

Vincristine is an essential component of many chemotherapy regimens, helping to reduce tumor size and improve survival rates in cancer patients.

General data about SINDOVIN 1mg

Substance:
vincristine
Date of latest medicines list:
01-06-2026
Product code:
W52220001
Concentration:
1mg
Pharmaceutical form:
powder for solution for injection / infusion
Quantity:
1
Product type:
Generic medicine
Price:
63.81 RON
Prescription status:
S — Medicines dispensed with a restricted medical prescription, reserved for use in certain specialized fields.

Concentrations available for vincristine

  • 1mg
  • 1mg/ml

Compensation lists for SINDOVIN 1mg Actavis

NHP 3 (C2) - NHP oncology

Price
63.81 RON
Copayment
61.02 RON
Patient
2.79 RON