Indicated for: dental or regional local anesthesia
Route of administration: injectable
Substance: mepivacaine + adrenaline (amide local anesthetic and adrenergic vasoconstrictor)
ATC: N01BB53 (Nervous system | Anesthetics, local | Amides)
Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.
This medicine may have important interactions with other medicines.
This medicine may increase the risk of heart rhythm disturbances.
Mepivacaine + adrenaline is an injectable combination used for local anaesthesia, especially in dental or minor surgical procedures. Mepivacaine temporarily blocks pain transmission through nerves, while adrenaline narrows local blood vessels, reducing bleeding and prolonging the duration of anaesthesia. It is administered by trained healthcare professionals.
The dose and injection technique are chosen by the doctor or dentist according to the procedure, body weight, age, general condition and associated illnesses. After dental anaesthesia, the patient should avoid biting the cheek, lip or tongue until numbness has worn off. Tell the clinician if you have had reactions to anaesthetics, fainting with injections or heart disease.
Side effects may include prolonged numbness, injection-site pain, dizziness, tremor, palpitations, anxiety, nausea or headache. Rare toxic reactions can occur if blood levels of the anaesthetic become too high: metallic taste, ringing in the ears, confusion, seizures, low blood pressure or rhythm disturbances. Adrenaline may intensify palpitations.
Seek immediate medical help if breathing difficulty, facial swelling, hives, chest pain, fainting, seizures, sudden weakness or persistent palpitations occur. In severe hypertension, rhythm disorders, hyperthyroidism or treatment with beta-blockers or antidepressants, the clinician will carefully assess the need for adrenaline and the maximum safe dose.