Medicine information RYBELSUS 14mg tablets

Product code:
W66743003
Quantity:
90
Indicated for:
type 2 diabetes mellitus; weight management
Route of administration:
oral
Substance:
semaglutide (GLP-1 receptor agonist)
ATC
A10BJ06 — Alimentary tract and metabolism | Blood glucose lowering drugs, excl. insulins | Glucagon-like peptide-1 (GLP-1) analogues
Semaglutide is a medication used to treat type 2 diabetes and, in some cases, to manage body weight in patients with obesity or overweight. It belongs to the class of GLP-1 receptor agonists (glucagon-like peptide-1), which work by stimulating insulin secretion, reducing glucagon secretion, and slowing gastric emptying, thereby lowering blood sugar levels and reducing appetite.

Semaglutide is available as a subcutaneous injection (administered once weekly) or, in some cases, as oral tablets. It is used in combination with a healthy diet and exercise to improve glycemic control and, in the case of obesity treatment, to support weight loss.

Common side effects include nausea, vomiting, diarrhea, constipation, and abdominal pain, especially at the start of treatment. In rare cases, it may cause pancreatitis, hypoglycemia (particularly when used with other antidiabetic medications), or thyroid problems.

Semaglutide is not recommended for patients with a history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN2). It is important for patients to follow their doctor's recommendations and monitor for any adverse reactions.

General data about RYBELSUS 14mg

Substance:
semaglutide
Date of latest medicines list:
01-10-2026
Product code:
W66743003
Strength:
14mg
Pharmaceutical form:
tablets
Quantity:
90
Product type:
Original
Price:
1380.38 RON
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
NOVO NORDISK A/S - DANEMARCA
Holder:
NOVO NORDISK A/S - DANEMARCA
Number:
1430/2020/10
Shelf life:
30 months

Pharmaceutical forms available for semaglutide

Strengths available for semaglutide

  • 0.25mg
  • 0.5mg
  • 1.34mg/ml
  • 1.5mg
  • 1.7mg
  • 14mg
  • 1mg
  • 2.4mg
  • 2.68mg/ml
  • 25mg
  • 3mg
  • 4mg
  • 7.2mg
  • 7mg
  • 9mg

Official documents

The SmPC text is not displayed because a match to this medicine, strength and pharmaceutical form has not been confirmed.

The correspondence between the document and the displayed text is unconfirmed.

Source institution
EMA
Document language
English
Source record: first published
27/05/2020
Source record: last updated
22/04/2026

Warnings:

Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning

Use during pregnancy only on medical advice.

Reimbursement lists for RYBELSUS 14mg Novo Nordisk

NHP 5 (C2) - Diabetes

Price
1380.38 RON
Copayment
1380.38 RON
Patient payment
0.00 RON