Indicated for: prevention and treatment of thromboembolism
Route of administration: injectable
Substance: desirudine (anticoagulant)
ATC: B01AE01 (Blood and blood forming organs | Antithrombotic agents | Direct thrombin inhibitors)
Dose adjustment may be needed in kidney disease.
This medicine may have important interactions with other medicines.
This medicine is subject to additional monitoring.
Use during breastfeeding only on medical advice.
Use during pregnancy only on medical advice.
This medicine may increase the risk of bleeding.
Desirudin is an anticoagulant used for the prevention of deep vein thrombosis in patients undergoing orthopedic surgeries, such as hip replacement. It works by directly inhibiting thrombin, preventing the formation of blood clots.
The medication is administered via subcutaneous injection, usually twice daily, with the dose adjusted based on the patient's weight and bleeding risk. Common side effects include bleeding, bruising at the injection site, and anemia.
Desirudin is contraindicated in patients with active bleeding, severe renal impairment, or hypersensitivity to the active substance. Its use also requires careful monitoring to prevent hemorrhagic complications.
This medication is an effective option for preventing thromboembolic complications, helping to reduce the risk of severe cardiovascular events.