Indicated for: obesity; weight management
Substance: amfepramone (psychostimulant)
ATC: A08AA03 (Alimentary tract and metabolism | Antiobesity preparations, excl. diet products | Centrally acting antiobesity products)
Amfepramone is a medication used as an adjunct in the treatment of obesity, particularly in patients who have not succeeded in losing weight through diet and exercise. It belongs to a class of drugs called anorectics and works by stimulating the central nervous system, reducing appetite, and increasing energy levels.
Amfepramone is taken orally, usually 30-60 minutes before meals, and treatment is recommended for short-term use, typically no more than a few weeks, to avoid the risk of dependence.
Side effects may include insomnia, nervousness, palpitations, increased blood pressure, and dry mouth. In rare cases, severe adverse reactions such as pulmonary hypertension or psychiatric disorders may occur.
Patients taking amfepramone should be closely monitored, and its use is contraindicated in individuals with cardiovascular conditions, severe hypertension, or a history of substance abuse. Additionally, the medication is not recommended during pregnancy or breastfeeding. Amfepramone can be a useful option for weight loss, but its use must be carefully supervised by a specialist physician.