Leaflet QUARELIN 400mg / 60mg / 40mg tablets

Indicated for: pain and inflammation

Route of administration: oral

Substance: metamizole sodium + caffeine + drotaverine (nonsteroidal anti-inflammatory drug + analgesic and antipyretic + gastrointestinal antispasmodic)

ATC: N02BB52 (Nervous system | Other analgesics and antipyretics | Pyrazolones)

Precautions:
Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Nephrotoxicity
Nephrotoxicity

This medicine may affect the kidneys.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Bleeding risk
Bleeding risk

This medicine may increase the risk of bleeding.

Ulcer / gastrointestinal bleeding
Ulcer / gastrointestinal bleeding

This medicine may increase the risk of ulcer or gastrointestinal bleeding.

The combination of metamizole sodium + caffeine + drotaverine is used to relieve moderate to severe pain, especially pain associated with smooth muscle spasms, such as biliary colic, renal colic, or menstrual pain. This combination provides rapid and effective pain relief by combining analgesic, antispasmodic, and stimulant effects.

- Metamizole sodium is an analgesic and antipyretic that reduces pain and fever by inhibiting prostaglandin synthesis.
- Caffeine acts as a central nervous system stimulant, enhancing the effectiveness of the analgesic and reducing fatigue associated with pain.
- Drotaverine is an antispasmodic that relaxes smooth muscles, effectively reducing pain caused by spasms.

This combination is indicated for the treatment of acute pain, such as migraines, tension headaches, colic, or menstrual pain.

Side effects may include nausea, dizziness, low blood pressure, palpitations, or allergic reactions. In rare cases, agranulocytosis (a decrease in white blood cells) or severe hypersensitivity reactions may occur. It is important to take this medication as prescribed by a doctor, and long-term use should be avoided.

QUARELIN 400mg/60mg/40mg tablets OPELLA HEALTHCARE RO, metamizole sodium+caffeine+drotaverine

General data about QUARELIN 400mg / 60mg / 40mg

  • Substance: metamizole sodium + caffeine + drotaverine
  • Date of latest medicines list: 01-06-2026
  • Product code: W67968001
  • Concentration: 400mg / 60mg / 40mg
  • Pharmaceutical form: tablets
  • Quantity: 10
  • Product type: Original
  • Price: 36.56 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: CHINOIN PHARMACEUTICAL & CHEMICAL WORKS CO. LTD - UNGARIA
  • Holder: OPELLA HEALTHCARE ROMANIA SRL - ROMANIA
  • Number: 11664/2019/01
  • Shelf life: 3 years