Leaflet PURI-NETHOL 50mg tablets

Indicated for: leukemia

Route of administration: oral

Substance: mercaptopurine (antimetabolite antineoplastic)

ATC: L01BB02 (Antineoplastic and immunomodulating agents | Antimetabolites | Purine analogues)

Precautions:
Fertility warning
Fertility warning

This medicine may affect fertility.

Dose adjustment in hepatic impairment
Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Cytotoxic / special handling
Cytotoxic / special handling

Handle with special care.

Contraception required
Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding
Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy
Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis
Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring
Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Severe skin reactions
Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Genetic test recommended
Genetic test recommended

A genetic test may be needed before treatment.

Mercaptopurine is a medication used for the treatment of acute lymphoblastic leukemia and other hematological conditions. It works by inhibiting DNA synthesis in cancer cells, thereby preventing their proliferation.

The medication is taken orally, as directed by a doctor, usually once daily. It is important for patients to follow the treatment regimen and undergo regular check-ups to monitor liver and hematologic function.

Patients should be aware of potential side effects, such as nausea, decreased blood cell counts, or liver impairment. It is important to inform the doctor of any unusual symptoms.

Common side effects include nausea, decreased blood cell counts, and liver impairment. In rare cases, severe reactions such as liver failure or severe infections may occur. Patients should be informed of these risks before use.

General data about PURI-NETHOL 50mg

  • Substance: mercaptopurine
  • Date of latest medicines list: 01-06-2026
  • Product code: W58868001
  • Concentration: 50mg
  • Pharmaceutical form: tablets
  • Quantity: 25
  • Product type: Original
  • Price: 67.74 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: EXCELLA GMBH & CO. KG - GERMANIA
  • Holder: ASPEN PHARMA TRADING LIMITED - IRLANDA
  • Number: 11277/2018/01
  • Shelf life: 5 years

Pharmaceutical forms available for mercaptopurine

Concentrations available for mercaptopurine

  • 20mg/ml
  • 50mg

Compensation lists for PURI-NETHOL 50mg Aspen

NHP 3 (C2) - NHP oncology

Price

Copayment

Patient

67.74 RON

67.74 RON

0.00 RON