Dose adjustment in renal impairment
Dose adjustment may be needed in kidney disease.
Leaflet PULPOMIXINE paste
- Product code:
- W05642001
- Quantity:
- 1
- Indicated for:
- bacterial infections with susceptible Gram-negative organisms
- Route of administration:
- cutaneous
- Substance:
- polymyxin (polypeptide antibiotic)
- ATC
- A01ACN1 — Alimentary tract and metabolism | Stomatological preparations | Stomatological preparations | Corticosteroids for local oral treatment
Precautions:
Anaphylaxis
Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.
Colitis / severe diarrhea
Seek medical advice if severe or persistent diarrhea occurs.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Nephrotoxicity
This medicine may affect the kidneys.
Ototoxicity
This medicine may affect hearing or balance.
Polymyxin is an antibiotic active mainly against certain Gram-negative bacteria. Depending on the exact substance and product form, it may be used locally for skin, eye or ear infections, while systemic forms are reserved for severe hospital-treated infections. It has no effect on viruses and should not be used without a clear medical indication.
Administration depends on the product: drops, ointment, topical solution or, rarely, injectable treatment in a specialised setting. It is important to follow the recommended duration and not stop too early when a full course has been prescribed. Do not use leftover antibiotic for new infections and do not share the bottle or tube with other people.
Local side effects may include stinging, burning, redness, itching, rash or contact dermatitis. With systemic treatment, important risks are kidney injury and hearing or balance problems, dizziness, tingling or muscle weakness, which is why monitoring and carefully calculated doses are required. Any history of antibiotic allergy should be reported.
Contact a doctor if symptoms worsen, swelling, intense pain, decreased vision, heavy discharge, fever or lack of improvement occurs. During systemic treatment, report reduced urination, hearing changes, severe dizziness or breathing difficulty immediately. Correct use helps limit bacterial resistance and reduces the risk of avoidable side effects.
Administration depends on the product: drops, ointment, topical solution or, rarely, injectable treatment in a specialised setting. It is important to follow the recommended duration and not stop too early when a full course has been prescribed. Do not use leftover antibiotic for new infections and do not share the bottle or tube with other people.
Local side effects may include stinging, burning, redness, itching, rash or contact dermatitis. With systemic treatment, important risks are kidney injury and hearing or balance problems, dizziness, tingling or muscle weakness, which is why monitoring and carefully calculated doses are required. Any history of antibiotic allergy should be reported.
Contact a doctor if symptoms worsen, swelling, intense pain, decreased vision, heavy discharge, fever or lack of improvement occurs. During systemic treatment, report reduced urination, hearing changes, severe dizziness or breathing difficulty immediately. Correct use helps limit bacterial resistance and reduces the risk of avoidable side effects.
General data about PULPOMIXINE
- Substance:
- polymyxin
- Date of latest medicines list:
- 01-07-2013
- Product code:
- W05642001
- Pharmaceutical form:
- paste
- Quantity:
- 1
- Product type:
- Generic medicine
- Prescription status:
- S — Medicines dispensed with a restricted medical prescription, reserved for use in certain specialized fields.