Dose adjustment in renal impairment
Dose adjustment may be needed in kidney disease.
Leaflet PROTHROMPLEX TOTAL 500UI powder and solvent for solution for injection
- Product code:
- W69668001
- Quantity:
- 1
- Indicated for:
- bleeding; coagulation disorders
- Route of administration:
- injectable
- Substance:
- coagulation factors (anticoagulant)
- ATC
- B02BD01 — Blood and blood forming organs | Vitamin k and other hemostatics | Blood coagulation factors
Precautions:
Major drug interactions
This medicine may have important interactions with other medicines.
Additional monitoring
This medicine is subject to additional monitoring.
Breastfeeding warning
Use during breastfeeding only on medical advice.
Pregnancy warning
Use during pregnancy only on medical advice.
Bleeding risk
This medicine may increase the risk of bleeding.
Coagulation factors are essential proteins involved in the process of stopping bleeding, playing a key role in blood clot formation. Deficiency or dysfunction of these factors can lead to bleeding disorders such as hemophilia or von Willebrand disease. Treatment with coagulation factors is used to prevent or stop bleeding in people with such conditions.
Coagulation factors are administered intravenously under medical supervision, with the dose determined by the severity of the deficiency and the type of bleeding event. Treatment can be given preventively or as needed, for example during surgeries or after injuries.
Side effects may include allergic reactions, fever, headaches, or, rarely, the development of antibodies that can reduce the effectiveness of the treatment. Careful monitoring of the patient is essential to quickly detect any adverse reactions and adjust the treatment if necessary.
Therapy with coagulation factors has significantly improved the quality of life for patients with bleeding disorders. Following medical advice and being informed about possible risks contribute to safe and effective treatment.
Coagulation factors are administered intravenously under medical supervision, with the dose determined by the severity of the deficiency and the type of bleeding event. Treatment can be given preventively or as needed, for example during surgeries or after injuries.
Side effects may include allergic reactions, fever, headaches, or, rarely, the development of antibodies that can reduce the effectiveness of the treatment. Careful monitoring of the patient is essential to quickly detect any adverse reactions and adjust the treatment if necessary.
Therapy with coagulation factors has significantly improved the quality of life for patients with bleeding disorders. Following medical advice and being informed about possible risks contribute to safe and effective treatment.
General data about PROTHROMPLEX TOTAL 500UI
- Substance:
- coagulation factors
- Date of latest medicines list:
- 01-06-2026
- Product code:
- W69668001
- Concentration:
- 500UI
- Pharmaceutical form:
- powder and solvent for solution for injection
- Quantity:
- 1
- Product type:
- Original
- Price:
- 1382.79 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for coagulation factors
Concentrations available for coagulation factors
- 1000UI
- 500UI
- 600UI