PROGRAF 5mg capsules medication leaflet

L04AD02 • tacrolimus • Antineoplastic and immunomodulating agents | Immunosuppressants | Calcineurin inhibitors

Tacrolimus is an immunosuppressive medication used to prevent organ rejection in transplant recipients, such as kidney, liver, or heart transplants. It works by inhibiting the activity of T-cells in the immune system, thereby reducing the immune response that could attack the transplanted organ.

Tacrolimus is available in capsules, ointments, and injectable solutions. For transplants, it is administered long-term to ensure the proper functioning of the transplanted organ. Additionally, tacrolimus ointment is used to treat severe atopic dermatitis when other treatments are ineffective.

The medication requires careful monitoring, as high levels can lead to toxicity, while low levels may increase the risk of organ rejection. Common side effects include tremors, headaches, high blood pressure, nausea, and an increased risk of infections.

Tacrolimus should be used as directed by a healthcare provider, and patients are advised to avoid excessive sun exposure, as the medication can increase skin sensitivity.