Avoid grapefruit
Avoid grapefruit and grapefruit juice.
Leaflet PROGRAF 5mg capsules
- Product code:
- W53731001
- Quantity:
- 50
- Indicated for:
- prevention of transplant rejection
- Route of administration:
- oral
- Substance:
- tacrolimus (immunosuppressant)
- ATC
- L04AD02 — Antineoplastic and immunomodulating agents | Immunosuppressants | Immunosuppressants | Calcineurin inhibitors
Precautions:
Avoid live vaccines
Avoid live vaccines during treatment if contraindicated.
Immunosuppression / infection risk
This medicine may increase the risk of infections.
Narrow therapeutic index
The dose must be followed strictly.
Major drug interactions
This medicine may have important interactions with other medicines.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Breastfeeding warning
Use during breastfeeding only on medical advice.
Pregnancy warning
Use during pregnancy only on medical advice.
Tacrolimus is an immunosuppressive medication used to prevent organ rejection in transplant recipients, such as kidney, liver, or heart transplants. It works by inhibiting the activity of T-cells in the immune system, thereby reducing the immune response that could attack the transplanted organ.
Tacrolimus is available in capsules, ointments, and injectable solutions. For transplants, it is administered long-term to ensure the proper functioning of the transplanted organ. Additionally, tacrolimus ointment is used to treat severe atopic dermatitis when other treatments are ineffective.
The medication requires careful monitoring, as high levels can lead to toxicity, while low levels may increase the risk of organ rejection. Common side effects include tremors, headaches, high blood pressure, nausea, and an increased risk of infections.
Tacrolimus should be used as directed by a healthcare provider, and patients are advised to avoid excessive sun exposure, as the medication can increase skin sensitivity.
Tacrolimus is available in capsules, ointments, and injectable solutions. For transplants, it is administered long-term to ensure the proper functioning of the transplanted organ. Additionally, tacrolimus ointment is used to treat severe atopic dermatitis when other treatments are ineffective.
The medication requires careful monitoring, as high levels can lead to toxicity, while low levels may increase the risk of organ rejection. Common side effects include tremors, headaches, high blood pressure, nausea, and an increased risk of infections.
Tacrolimus should be used as directed by a healthcare provider, and patients are advised to avoid excessive sun exposure, as the medication can increase skin sensitivity.
General data about PROGRAF 5mg
- Substance:
- tacrolimus
- Date of latest medicines list:
- 01-06-2026
- Product code:
- W53731001
- Concentration:
- 5mg
- Pharmaceutical form:
- capsules
- Quantity:
- 50
- Product type:
- Original
- Price:
- 1089.23 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for tacrolimus
Concentrations available for tacrolimus
- 0.03%
- 0.1%
- 0.2mg
- 0.5mg
- 1mg
- 2mg
- 3mg
- 5mg
- 5mg/ml
Compensation lists for PROGRAF 5mg Astellas
NHP 9.4 (C2) - Kidney transplant, combined kidney and pancreas transplant
- Price
- 1089.23 RON
- Copayment
- 1089.23 RON
- Patient
- 0.00 RON
NHP 9.7 (C2) - Outpatient treatment of transplant patients
- Price
- 1089.23 RON
- Copayment
- 1089.23 RON
- Patient
- 0.00 RON