PREAMLESSA 5.7mg / 5mg tablets medication leaflet

C09BB04 • perindopril + amlodipine • Cardiovascular system | Ace inhibitors, combinations | Ace inhibitors and calcium channel blockers

The combination of perindopril and amlodipine is used to treat essential hypertension (high blood pressure) and stable coronary artery disease. It helps lower blood pressure and prevent cardiovascular complications such as heart attack or stroke.

Perindopril is an angiotensin-converting enzyme (ACE) inhibitor that relaxes blood vessels, lowers blood pressure, and reduces the workload on the heart. Amlodipine is a calcium channel blocker that dilates blood vessels, improving blood flow and reducing blood pressure.

This combination is recommended for patients requiring combination therapy to control blood pressure or reduce symptoms of angina pectoris (chest pain caused by insufficient blood flow to the heart). Through the synergistic action of the two components, the treatment provides more effective blood pressure control and cardiovascular protection.

Side effects may include dizziness, headache, swelling (especially in the ankles), nausea, fatigue, or palpitations. In rare cases, allergic reactions, severe hypotension, or kidney problems may occur. Regular medical monitoring is essential to adjust the treatment if necessary.

Patients should strictly follow their doctor’s instructions regarding dosage and avoid excessive salt or alcohol consumption. It is also recommended to inform the doctor about other medications being taken or pre-existing conditions, such as kidney or liver impairment.