Glaucoma warning
Use caution if you have glaucoma or increased eye pressure.
Leaflet PIAFEN tablets
- Product code:
- W01509003
- Quantity:
- 10
- Indicated for:
- pain and inflammation
- Route of administration:
- oral
- Substance:
- metamizole sodium + pitofenone hydrochloride + bromomethyl fenpipramide (nonsteroidal anti-inflammatory drug + analgesic and antipyretic)
- ATC
- A03DA02 — Alimentary tract and metabolism | Antispasmodics in combination with analgesics | Synthetic anticholinergic agents in combination with analgesics
Precautions:
Anticholinergic effects
May cause dry mouth, constipation, urinary retention, or blurred vision.
Major drug interactions
This medicine may have important interactions with other medicines.
Nephrotoxicity
This medicine may affect the kidneys.
Pregnancy warning
Use during pregnancy only on medical advice.
Elderly warning
Older people may have an increased risk of side effects.
Bleeding risk
This medicine may increase the risk of bleeding.
Ulcer / gastrointestinal bleeding
This medicine may increase the risk of ulcer or gastrointestinal bleeding.
This combination of metamizole sodium, pitofenone hydrochloride, and fenpibromide bromomethylate is used to relieve acute moderate to severe pain, especially spasmodic pain such as renal, biliary, or intestinal colic. It has analgesic, antispasmodic, and anti-inflammatory properties.
Metamizole sodium is an analgesic and antipyretic that reduces pain and fever. Pitofenone hydrochloride has a direct muscle-relaxing effect on smooth muscles, reducing spasms. Fenpibromide bromomethylate, an anticholinergic, enhances the antispasmodic effect by reducing involuntary muscle contractions.
This combination is effective in treating pain associated with spasms of internal organs, such as the gastrointestinal or urinary tract. It can also be used to relieve severe menstrual pain or other conditions involving muscle spasms.
Side effects may include dry mouth, dizziness, nausea, constipation, or allergic reactions. In rare cases, severe reactions such as low blood pressure, breathing difficulties, or serious skin reactions may occur. Patients should inform their doctor about any side effects or other medications they are taking.
Patients must strictly follow the dosage recommended by their doctor, as excessive use can lead to serious adverse effects. It is also contraindicated in certain conditions, such as severe renal or hepatic insufficiency or allergies to any of the components.
Metamizole sodium is an analgesic and antipyretic that reduces pain and fever. Pitofenone hydrochloride has a direct muscle-relaxing effect on smooth muscles, reducing spasms. Fenpibromide bromomethylate, an anticholinergic, enhances the antispasmodic effect by reducing involuntary muscle contractions.
This combination is effective in treating pain associated with spasms of internal organs, such as the gastrointestinal or urinary tract. It can also be used to relieve severe menstrual pain or other conditions involving muscle spasms.
Side effects may include dry mouth, dizziness, nausea, constipation, or allergic reactions. In rare cases, severe reactions such as low blood pressure, breathing difficulties, or serious skin reactions may occur. Patients should inform their doctor about any side effects or other medications they are taking.
Patients must strictly follow the dosage recommended by their doctor, as excessive use can lead to serious adverse effects. It is also contraindicated in certain conditions, such as severe renal or hepatic insufficiency or allergies to any of the components.
General data about PIAFEN
- Substance:
- metamizole sodium + pitofenone hydrochloride + bromomethyl fenpipramide
- Date of latest medicines list:
- 01-06-2026
- Product code:
- W01509003
- Pharmaceutical form:
- tablets
- Quantity:
- 10
- Product type:
- Generic medicine
- Price:
- 14.12 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Compensation lists for PIAFEN Antibiotice
C3 - Sublist C - section C3 (children, pregnant women and postpartum women) with 100% discount from the reference price
- Price
- 14.12 RON
- Copayment
- 5.87 RON
- Patient
- 8.25 RON