Leaflet PENICILINA G SODICA FRESENIUS KABI 1000000UI powder for solution for injection / infusion

Indicated for: bacterial infections

Route of administration: injectable / infusion

Substance: benzylpenicillin (penicillin antibiotic)

ATC: J01CE01 (Antiinfectives for systemic use | Beta-lactam antibacterials, penicillins | Beta-lactamase sensitive penicillins)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Anaphylaxis
Anaphylaxis

Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.

Colitis / severe diarrhea
Colitis / severe diarrhea

Seek medical advice if severe or persistent diarrhea occurs.

Benzylpenicillin, also known as penicillin G, is a beta-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is effective against Gram-positive bacteria such as streptococci, pneumococci, and sensitive staphylococci, as well as some Gram-negative bacteria like Neisseria meningitidis and Treponema pallidum (the causative agent of syphilis).

Benzylpenicillin is administered parenterally (intramuscularly or intravenously) because it is inactivated by gastric acid if taken orally. It is used to treat conditions such as bacterial pneumonia, endocarditis, meningitis, syphilis, erysipelas, and other severe infections.

Adverse effects may include allergic reactions, ranging from skin rashes to severe anaphylactic reactions. Other possible side effects include nausea, diarrhea, pain at the injection site, and, in rare cases, hematological disorders or neurotoxicity (at high doses).

Benzylpenicillin is contraindicated in patients with known hypersensitivity to penicillins or other beta-lactam antibiotics. It should be used with caution in patients with renal impairment or a history of multiple allergies. During pregnancy, it may be administered if the benefits outweigh the risks, but its use should be closely monitored by a doctor.

General data about PENICILINA G SODICA FRESENIUS KABI 1000000UI

  • Substance: benzylpenicillin
  • Date of latest medicines list: 01-06-2026
  • Product code: W70237001
  • Concentration: 1000000UI
  • Pharmaceutical form: powder for solution for injection / infusion
  • Quantity: 10
  • Product type: Generic medicine
  • Price: 152.34 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: LABESFAL-LABORATORIOS ALMIRO, S.A. - PORTUGALIA
  • Holder: FRESENIUS KABI ROMANIA S.R.L. - ROMANIA
  • Number: 15412/2024/01
  • Shelf life: 2 years

Pharmaceutical forms available for benzylpenicillin

Concentrations available for benzylpenicillin

  • 1000000UI
  • 400000UI
  • 5000000ui

Compensation lists for PENICILINA G SODICA FRESENIUS KABI 1000000UI Karo

G30 (C1) - Venereal diseases

Price

Copayment

Patient

152.34 RON

134.63 RON

17.71 RON

GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)

Price

Copayment

Patient

152.34 RON

134.63 RON

17.71 RON