Dose adjustment in renal impairment
Dose adjustment may be needed in kidney disease.
Leaflet PENICILINA G SODICA 5000000ui powder for solution for injection
- Product code:
- W00577003
- Quantity:
- 1
- Indicated for:
- bacterial infections
- Route of administration:
- injectable
- Substance:
- benzylpenicillin (penicillin antibiotic)
- ATC
- J01CE01 — Antiinfectives for systemic use | Beta-lactam antibacterials, penicillins | Beta-lactamase sensitive penicillins
Precautions:
Anaphylaxis
Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.
Colitis / severe diarrhea
Seek medical advice if severe or persistent diarrhea occurs.
Benzylpenicillin, also known as penicillin G, is a beta-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is effective against Gram-positive bacteria such as streptococci, pneumococci, and sensitive staphylococci, as well as some Gram-negative bacteria like Neisseria meningitidis and Treponema pallidum (the causative agent of syphilis).
Benzylpenicillin is administered parenterally (intramuscularly or intravenously) because it is inactivated by gastric acid if taken orally. It is used to treat conditions such as bacterial pneumonia, endocarditis, meningitis, syphilis, erysipelas, and other severe infections.
Adverse effects may include allergic reactions, ranging from skin rashes to severe anaphylactic reactions. Other possible side effects include nausea, diarrhea, pain at the injection site, and, in rare cases, hematological disorders or neurotoxicity (at high doses).
Benzylpenicillin is contraindicated in patients with known hypersensitivity to penicillins or other beta-lactam antibiotics. It should be used with caution in patients with renal impairment or a history of multiple allergies. During pregnancy, it may be administered if the benefits outweigh the risks, but its use should be closely monitored by a doctor.
Benzylpenicillin is administered parenterally (intramuscularly or intravenously) because it is inactivated by gastric acid if taken orally. It is used to treat conditions such as bacterial pneumonia, endocarditis, meningitis, syphilis, erysipelas, and other severe infections.
Adverse effects may include allergic reactions, ranging from skin rashes to severe anaphylactic reactions. Other possible side effects include nausea, diarrhea, pain at the injection site, and, in rare cases, hematological disorders or neurotoxicity (at high doses).
Benzylpenicillin is contraindicated in patients with known hypersensitivity to penicillins or other beta-lactam antibiotics. It should be used with caution in patients with renal impairment or a history of multiple allergies. During pregnancy, it may be administered if the benefits outweigh the risks, but its use should be closely monitored by a doctor.
General data about PENICILINA G SODICA 5000000ui
- Substance:
- benzylpenicillin
- Date of latest medicines list:
- 01-07-2013
- Product code:
- W00577003
- Concentration:
- 5000000ui
- Pharmaceutical form:
- powder for solution for injection
- Quantity:
- 1
- Product type:
- Generic medicine
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for benzylpenicillin
Concentrations available for benzylpenicillin
- 1000000UI
- 400000UI
- 5000000ui