PANZYGA 100mg / ml solution for infusion medication leaflet

J06BA02 • normal immunoglobulin for intravascular administration • Antiinfectives for systemic use | Immunoglobulins | Immunoglobulins, normal human

Normal immunoglobulin for intravenous administration (IVIG) is a product derived from human plasma, used to treat a variety of conditions involving immune system deficiencies or autoimmune disorders. It contains antibodies (immunoglobulin G - IgG) that help support or regulate the body's immune response.

IVIG is used to treat conditions such as:

- Primary antibody deficiencies (e.g., agammaglobulinemia or common variable immunodeficiency).
- Autoimmune diseases, such as idiopathic thrombocytopenic purpura (ITP), Guillain-Barré syndrome, or chronic inflammatory demyelinating polyneuropathy (CIDP).
- Severe infections or infection prevention in immunocompromised patients.

It is administered via intravenous infusion, typically in a hospital or under strict medical supervision. The dosage and frequency of treatment depend on the condition being treated and the patient's response.

Common side effects include headache, fever, chills, nausea, fatigue, or infusion site reactions. Rarely, severe reactions may occur, such as allergic reactions, kidney dysfunction, or thrombosis. Therefore, patients must be closely monitored during and after administration.

IVIG is a critical treatment for many immune-related conditions, but its use requires careful assessment of risks and benefits, especially in patients with a history of kidney failure, cardiovascular diseases, or allergies to plasma proteins.